Across TCGA patient cohorts, HELT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,579 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HELT-associated GO terms across cancer lineages are Outer mitochondrial membrane organization, Spindle organization, and Mitochondrial translation. Each is linked with HELT in more than 11 cancer types. Because this analysis shows association rather than direction, both HELT-to-partner and partner-to-HELT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HELT→partner) and Y-score (partner→HELT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Outer mitochondrial membrane organization →	+0.056	+0.082	<.001	<.001	3	12
STAD	Spindle organization →	+0.062	+0.093	<.001	<.001	3	12
STAD	Mitochondrial translation →	+0.066	+0.092	<.001	<.001	3	11
STAD	Protein K11-linked ubiquitination →	+0.054	+0.087	<.001	<.001	3	11
STAD	Microtubule cytoskeleton organization involved in mitosis →	+0.068	+0.084	<.001	<.001	3	11
STAD	Positive regulation of DNA metabolic process →	+0.060	+0.091	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,579 associations by consensus.

Exploration

HELT survival (RNA) · tumor vs normal (RNA) · all HELT data types