HELB

Across TCGA patient cohorts, HELB RNA expression is significantly associated with the protein abundance of many other proteins, with 10,179 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HELB-associated proteins across cancer lineages are ARHGAP45, WAS, and STK4. Each is linked with HELB in more than 5 cancer types. Because this analysis shows association rather than direction, both HELB-to-partner and partner-to-HELB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HELB versus ARHGAP45 in COAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HELB→partner) and Y-score (partner→HELB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ARHGAP45 →	+0.464	+0.605	<.001	<.001	3	6
GBM	WAS →	+0.526	+0.546	<.001	<.001	3	6
HNSC	STK4 →	+0.408	+0.747	<.001	<.001	3	6
GBM	MYO1F →	+0.495	+0.472	.003	.005	3	5
GBM	MYO1G →	+0.512	+0.526	<.001	<.001	3	5
CCRCC	NFATC2 →	+0.374	+0.379	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,179 associations by consensus.

HELB vs ARHGAP45 — COAD

Explore this scatter interactively →