HEG1

Across TCGA patient cohorts, HEG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,180 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HEG1-associated proteins across cancer lineages are LMCD1, CCDC80, and AEBP1. Each is linked with HEG1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HEG1-to-partner and partner-to-HEG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEG1 versus LMCD1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEG1→partner) and Y-score (partner→HEG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LMCD1 →	+0.808	+1.461	<.001	<.001	3	10
BRCA	CCDC80 →	+0.846	+1.137	<.001	<.001	3	9
CCRCC	AEBP1 →	+0.832	+0.631	<.001	<.001	3	9
OV	CLEC3B →	+0.915	+1.228	<.001	.003	3	9
BRCA	CNN3 →	+0.600	+0.850	<.001	<.001	3	9
COAD	COL1A1 →	+0.890	+1.022	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,180 associations by consensus.

HEG1 vs LMCD1 — OV

Explore this scatter interactively →