HECW2

Across TCGA patient cohorts, HECW2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,203 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HECW2-associated proteins across cancer lineages are HECW2_S852, ITIH1, and LAMA4. Each is linked with HECW2 in more than 7 cancer types. Because this analysis shows association rather than direction, both HECW2-to-partner and partner-to-HECW2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HECW2 versus HECW2_S852 in UCEC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HECW2→partner) and Y-score (partner→HECW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HECW2_S852 →	+0.814	+0.816	.004	<.001	3	8
UCEC	ITIH1 →	+0.627	+0.707	<.001	<.001	3	7
OV	LAMA4 →	+0.643	+0.498	<.001	<.001	3	7
GBM	EHD3 →	+0.563	+0.745	<.001	<.001	3	7
CCRCC	FMNL3 →	+0.443	+1.122	<.001	<.001	3	7
CCRCC	MMRN2 →	+0.614	+0.996	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,203 associations by consensus.

HECW2 vs HECW2_S852 — UCEC

Explore this scatter interactively →