HECTD1

Across TCGA patient cohorts, HECTD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,295 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HECTD1-associated proteins across cancer lineages are STRN3, FKBP3, and PARVG. Each is linked with HECTD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HECTD1-to-partner and partner-to-HECTD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HECTD1 versus STRN3 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HECTD1→partner) and Y-score (partner→HECTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STRN3 →	+0.377	+0.761	<.001	<.001	3	8
LUAD	FKBP3 →	+0.423	+0.385	<.001	<.001	3	8
GBM	PARVG →	-0.489	-0.227	<.001	<.001	3	7
GBM	PPP2R5E →	+0.311	+0.454	<.001	<.001	3	6
GBM	ARHGAP30 →	-0.531	-0.281	<.001	<.001	3	6
GBM	THEMIS2 →	-0.416	-0.256	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,295 associations by consensus.

HECTD1 vs STRN3 — HNSC

Explore this scatter interactively →