HECA

Across TCGA patient cohorts, HECA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,120 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HECA-associated proteins across cancer lineages are VTA1, PREP, and TLN1. Each is linked with HECA in more than 5 cancer types. Because this analysis shows association rather than direction, both HECA-to-partner and partner-to-HECA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HECA versus VTA1 in PDAC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HECA→partner) and Y-score (partner→HECA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VTA1 →	+0.260	+0.291	<.001	<.001	3	6
GBM	PREP →	+0.335	+0.589	<.001	<.001	3	5
OV	TLN1 →	+0.262	+0.461	.001	.005	3	5
BRCA	REPS1 →	+0.216	+0.402	.001	.005	3	5
GBM	EPB41L2 →	+0.314	+0.411	<.001	<.001	3	5
BRCA	RBM47 →	-0.270	-0.349	.005	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,120 associations by consensus.

HECA vs VTA1 — PDAC

Explore this scatter interactively →