HEATR9

Across TCGA cell cohorts, HEATR9 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,418 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HEATR9-associated GO terms across cancer lineages are Microtubule polymerization, Microtubule polymerization or depolymerization, and Microtubule nucleation. Each is linked with HEATR9 in more than 7 cancer types. Because this analysis shows association rather than direction, both HEATR9-to-partner and partner-to-HEATR9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by HEATR9-low versus HEATR9-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR9→partner) and Y-score (partner→HEATR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Microtubule polymerization →	+0.053	+0.013	.003	.001	3	8
SOFT_TISSUE	Microtubule polymerization or depolymerization →	+0.069	+0.020	<.001	.006	3	8
SOFT_TISSUE	Microtubule nucleation →	+0.081	+0.024	.001	.002	3	7
CNS	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.080	+0.016	<.001	.001	3	7
SOFT_TISSUE	Monocarboxylic acid biosynthetic process →	-0.036	-0.018	.004	.003	3	6
CNS	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.098	+0.018	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,418 associations by consensus.

Microtubule polymerization by HEATR9 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →