HEATR5B

Across TCGA patient cohorts, HEATR5B protein abundance is significantly associated with the RNA expression of many other genes, with 22,888 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEATR5B-associated genes across cancer lineages are FAP, TGFB3, and AFTPH. Each is linked with HEATR5B in more than 8 cancer types. Because this analysis shows association rather than direction, both HEATR5B-to-partner and partner-to-HEATR5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEATR5B versus FAP in OV, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR5B→partner) and Y-score (partner→HEATR5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAP →	-1.844	-0.175	<.001	.002	2	9
OV	TGFB3 →	-1.475	-0.229	<.001	<.001	3	7
OV	AFTPH →	+0.552	+0.233	<.001	<.001	3	7
OV	GLT8D2 →	-1.168	-0.169	.002	.007	2	8
OV	DACT1 →	-1.165	-0.225	<.001	<.001	3	7
OV	CLMP →	-1.202	-0.174	<.001	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,888 associations by consensus.

HEATR5B vs FAP — OV

Explore this scatter interactively →