HEATR5B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HEATR5B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,175 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HEATR5B-associated GO terms across cancer lineages are Cytosolic transport, Establishment of protein localization to vacuole, and Endosomal transport. Each is linked with HEATR5B in more than 17 cancer types. Because this analysis shows association rather than direction, both HEATR5B-to-partner and partner-to-HEATR5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by HEATR5B-low versus HEATR5B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR5B→partner) and Y-score (partner→HEATR5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYCytosolic transport →+0.076+0.716.001<.001318
OVARYEstablishment of protein localization to vacuole →+0.079+0.648<.001<.001317
UPPER_AERODIGESTIVE_TRACTEndosomal transport →+0.068+0.925<.001<.001315
OESOPHAGUSRetrograde transport, endosome to Golgi →+0.064+0.678.006.002315
UPPER_AERODIGESTIVE_TRACTProtein targeting to vacuole →+0.082+0.719<.001<.001315
KIDNEYGolgi organization →+0.055+0.565.003<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,175 associations by consensus.

Cytosolic transport by HEATR5B expression — KIDNEY

Box plot of Cytosolic transport in HEATR5B-low vs HEATR5B-high samples in KIDNEY.

Explore this box plot interactively →

Exploration