Across TCGA patient cohorts, HEATR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,295 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEATR4-associated proteins across cancer lineages are ALDH6A1, MTA1, and TCIRG1. Each is linked with HEATR4 in more than 4 cancer types. Because this analysis shows association rather than direction, both HEATR4-to-partner and partner-to-HEATR4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR4→partner) and Y-score (partner→HEATR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ALDH6A1 →	+0.490	+0.435	<.001	<.001	3	5
LSCC	MTA1 →	+0.339	+0.494	<.001	<.001	3	5
GBM	TCIRG1 →	-0.497	-0.500	.001	<.001	3	5
GBM	RALGAPA1 →	+0.341	+0.499	<.001	<.001	3	5
PDAC	SMARCC2_S347 →	+0.806	+0.280	.001	.004	3	5
LSCC	ILF2 →	+0.215	+0.531	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,295 associations by consensus.

Exploration

HEATR4 survival (RNA) · tumor vs normal (RNA) · all HEATR4 data types