HEATR3

Across TCGA patient cohorts, HEATR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,303 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEATR3-associated proteins across cancer lineages are OGFOD1, NUFIP2, and WWP2. Each is linked with HEATR3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HEATR3-to-partner and partner-to-HEATR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEATR3 versus OGFOD1 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR3→partner) and Y-score (partner→HEATR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OGFOD1 →	+0.437	+0.551	.004	.004	3	6
LSCC	NUFIP2 →	+0.227	+0.374	<.001	<.001	3	5
BRCA	WWP2 →	+0.328	+0.380	<.001	<.001	3	5
HNSC	CSNK2A2 →	+0.275	+0.500	<.001	<.001	3	4
LSCC	SPAST →	+0.223	+0.218	.007	.004	3	4
LSCC	CUL1 →	+0.289	+0.481	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,303 associations by consensus.

HEATR3 vs OGFOD1 — OV

Explore this scatter interactively →