HEATR3

Across TCGA cell cohorts, HEATR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,369 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HEATR3-associated GO terms across cancer lineages are Erythrocyte maturation, IMP biosynthetic process, and Positive regulation of nuclear cell cycle DNA replication. Each is linked with HEATR3 in more than 17 cancer types. Because this analysis shows association rather than direction, both HEATR3-to-partner and partner-to-HEATR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocyte maturation grouped by HEATR3-low versus HEATR3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR3→partner) and Y-score (partner→HEATR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Erythrocyte maturation →	+0.123	+0.875	<.001	<.001	3	18
OVARY	IMP biosynthetic process →	+0.194	+1.097	<.001	<.001	3	17
PANCREAS	Positive regulation of nuclear cell cycle DNA replication →	+0.151	+0.804	<.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.093	+0.977	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.094	+1.103	<.001	<.001	3	15
PANCREAS	Mitotic chromosome movement towards spindle pole →	+0.135	+1.142	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,369 associations by consensus.

Erythrocyte maturation by HEATR3 expression — OVARY

Explore this box plot interactively →