HEATR1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HEATR1 protein abundance is significantly associated with the RNA expression of many other genes, with 21,663 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEATR1-associated genes across cancer lineages are MYBL2, CPSF3, and HROB. Each is linked with HEATR1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HEATR1-to-partner and partner-to-HEATR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEATR1 versus MYBL2 in BRCA, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR1→partner) and Y-score (partner→HEATR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMYBL2 →+1.377+0.298<.001<.00139
LSCCCPSF3 →+0.650+0.426<.001<.00139
LSCCHROB →+0.960+0.447<.001<.00139
BRCASLC5A6 →+1.058+0.409<.001<.00139
OVABCA8 →-1.156-0.361<.001<.00139
OVLMOD1 →-1.266-0.273<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,663 associations by consensus.

HEATR1 vs MYBL2 — BRCA

Per-sample scatter of HEATR1 vs MYBL2 in BRCA (Pearson r = 0.55).

Explore this scatter interactively →

Exploration