HDLBP

Across TCGA patient cohorts, HDLBP protein abundance is significantly associated with the RNA expression of many other genes, with 20,998 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HDLBP-associated genes across cancer lineages are KDELR3, COL1A1, and TDO2. Each is linked with HDLBP in more than 5 cancer types. Because this analysis shows association rather than direction, both HDLBP-to-partner and partner-to-HDLBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDLBP versus KDELR3 in CCRCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDLBP→partner) and Y-score (partner→HDLBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KDELR3 →	+0.898	+0.243	<.001	<.001	3	6
GBM	COL1A1 →	+2.319	+0.241	<.001	<.001	3	6
GBM	TDO2 →	+1.520	+0.334	<.001	<.001	3	6
GBM	GPX8 →	+1.071	+0.241	<.001	<.001	3	6
BRCA	TMEM45A →	+1.085	+0.234	.003	<.001	3	6
LSCC	NUMA1 →	-0.633	-0.346	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,998 associations by consensus.

HDLBP vs KDELR3 — CCRCC

Explore this scatter interactively →