HDHD5

Across TCGA cell cohorts, HDHD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,493 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HDHD5-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Positive regulation of macrophage proliferation. Each is linked with HDHD5 in more than 13 cancer types. Because this analysis shows association rather than direction, both HDHD5-to-partner and partner-to-HDHD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by HDHD5-low versus HDHD5-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HDHD5→partner) and Y-score (partner→HDHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Symbiont-mediated disruption of host cellular anatomical structure →	+0.137	+0.839	<.001	<.001	3	13
SKIN	Symbiont-mediated disruption of host anatomical structure →	+0.137	+0.839	<.001	<.001	3	13
OVARY	Positive regulation of macrophage proliferation →	+0.198	+1.179	<.001	<.001	3	13
BONE	Ribosome assembly →	+0.118	+1.258	<.001	.001	3	12
URINARY_TRACT	IMP biosynthetic process →	+0.177	+0.975	.009	<.001	1	14
PANCREAS	DNA replication checkpoint signaling →	+0.148	+0.962	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,493 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by HDHD5 expression — SKIN

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