HDHD3

Across TCGA patient cohorts, HDHD3 RNA expression is significantly associated with the RNA expression of many other genes, with 17,679 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible HDHD3-associated genes across cancer lineages are FBXW5, PTGES2, and SH3GLB2. Each is linked with HDHD3 in more than 29 cancer types. Because this analysis shows association rather than direction, both HDHD3-to-partner and partner-to-HDHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDHD3 versus FBXW5 in READ, with a Pearson correlation of 0.67.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDHD3→partner) and Y-score (partner→HDHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	FBXW5 →	+0.801	+0.613	<.001	<.001	3	30
READ	PTGES2 →	+0.779	+0.658	<.001	<.001	3	29
UCS	SH3GLB2 →	+0.864	+0.718	<.001	<.001	3	29
SCLC	TUBB4B →	+1.135	+0.590	<.001	.001	3	29
KICH	ANAPC2 →	+0.790	+0.759	<.001	<.001	3	29
CHOL	SURF1 →	+0.605	+0.765	.001	.002	2	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,679 associations by consensus.

HDHD3 vs FBXW5 — READ

Explore this scatter interactively →