HDHD3

Across TCGA patient cohorts, HDHD3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,161 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HDHD3-associated genes across cancer lineages are BSPRY, MANSC1, and ALAD. Each is linked with HDHD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both HDHD3-to-partner and partner-to-HDHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDHD3 versus BSPRY in OV, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDHD3→partner) and Y-score (partner→HDHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BSPRY →	+1.166	+0.482	<.001	<.001	3	8
UCEC	MANSC1 →	+0.714	+0.271	.001	.007	3	5
UCEC	ALAD →	+0.599	+0.341	<.001	<.001	3	5
GBM	SAMD12 →	+0.686	+0.266	<.001	.003	3	5
HNSC	GALNT12 →	+0.947	+0.257	<.001	<.001	3	5
LSCC	CYP4F3 →	+2.269	+0.212	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,161 associations by consensus.

HDHD3 vs BSPRY — OV

Explore this scatter interactively →