HDHD3

Across TCGA cell cohorts, HDHD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,382 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HDHD3-associated GO terms across cancer lineages are Muscle organ development, Response to platinum ion, and Response to vitamin B1. Each is linked with HDHD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both HDHD3-to-partner and partner-to-HDHD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle organ development grouped by HDHD3-low versus HDHD3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HDHD3→partner) and Y-score (partner→HDHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Muscle organ development →	-0.075	-0.694	<.001	.003	3	13
STOMACH	Response to platinum ion →	+0.139	+1.261	.001	.001	3	12
LUNG_SCLC	Response to vitamin B1 →	+0.142	+0.742	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Response to aluminum ion →	+0.146	+1.448	<.001	<.001	3	10
STOMACH	Response to molecule of fungal origin →	+1.291	+1.536	.008	.002	3	10
BREAST	Collagen fibril organization →	-0.233	-0.991	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,382 associations by consensus.

Muscle organ development by HDHD3 expression — SOFT_TISSUE

Explore this box plot interactively →