Across TCGA pan-cancer cohorts, HDGFP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HDGFP1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where HDGFP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HDGFP1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

STAD, BRCA, and LUSC are the cancer types where HDGFP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HDGFP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.614	.004	4	view →
BRCA	All	All	+0.595	<.001	4	view →
LUSC	All	All	+0.662	.023	2	view →
KICH	Male	All	−1.350	.017	1	view →
LIHC	All	All	+0.498	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: HDGFP1 RNA expression & survival · all HDGFP1 data types