HDGFL3

Across TCGA patient cohorts, HDGFL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,215 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDGFL3-associated proteins across cancer lineages are SEC24A, RPL3, and RPL5. Each is linked with HDGFL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HDGFL3-to-partner and partner-to-HDGFL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGFL3 versus SEC24A in HNSC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGFL3→partner) and Y-score (partner→HDGFL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEC24A →	-0.294	-0.758	<.001	<.001	3	6
GBM	RPL3 →	-0.311	-0.388	<.001	<.001	3	5
CCRCC	RPL5 →	-0.253	-0.597	<.001	<.001	3	5
GBM	RPL7 →	-0.349	-0.315	<.001	<.001	3	5
GBM	RPS3A →	-0.221	-0.387	<.001	<.001	3	5
GBM	RPS8 →	-0.401	-0.544	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,215 associations by consensus.

HDGFL3 vs SEC24A — HNSC

Explore this scatter interactively →