HDGFL1

Across TCGA patient cohorts, HDGFL1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,920 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HDGFL1-associated genes across cancer lineages are DNMT3L, CD96, and EIF1. Each is linked with HDGFL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HDGFL1-to-partner and partner-to-HDGFL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGFL1 versus DNMT3L in CCRCC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGFL1→partner) and Y-score (partner→HDGFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DNMT3L →	+0.113	+0.335	<.001	.009	3	1
CCRCC	CD96 →	-0.887	-0.192	.003	.004	3	1
CCRCC	EIF1 →	+0.633	+0.265	.007	.008	3	1
CCRCC	RTP2 →	-0.408	-0.333	.002	.007	3	1
CCRCC	RNU6-132P →	+0.959	+0.338	.002	.006	3	1
CCRCC	IGHD5-12 →	-2.193	-0.333	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,920 associations by consensus.

HDGFL1 vs DNMT3L — CCRCC

Explore this scatter interactively →