HDGF

Across TCGA patient cohorts, HDGF protein abundance is significantly associated with the RNA expression of many other genes, with 12,635 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HDGF-associated genes across cancer lineages are C1orf43, TOMM20, and ZNF687. Each is linked with HDGF in more than 7 cancer types. Because this analysis shows association rather than direction, both HDGF-to-partner and partner-to-HDGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGF versus C1orf43 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGF→partner) and Y-score (partner→HDGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C1orf43 →	+0.647	+0.337	<.001	<.001	3	8
OV	TOMM20 →	+0.640	+0.520	.001	<.001	3	8
HNSC	ZNF687 →	+0.737	+0.349	<.001	<.001	3	8
HNSC	CLK2 →	+0.625	+0.328	<.001	<.001	3	8
UCEC	DAP3 →	+0.607	+0.260	<.001	<.001	3	7
LSCC	MRPL9 →	+0.614	+0.343	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,635 associations by consensus.

HDGF vs C1orf43 — HNSC

Explore this scatter interactively →