HDGF

Across TCGA cell cohorts, HDGF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,506 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HDGF-associated GO terms across cancer lineages are Spindle elongation, DNA replication checkpoint signaling, and Mitotic chromosome condensation. Each is linked with HDGF in more than 11 cancer types. Because this analysis shows association rather than direction, both HDGF-to-partner and partner-to-HDGF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by HDGF-low versus HDGF-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGF→partner) and Y-score (partner→HDGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Spindle elongation →	+0.225	+1.304	<.001	<.001	3	12
SOFT_TISSUE	DNA replication checkpoint signaling →	+0.148	+0.990	.003	<.001	3	12
BLOOD_Lymphoma	Mitotic chromosome condensation →	+0.130	+1.371	<.001	<.001	3	11
BREAST	Regulatory ncRNA processing →	+0.079	+1.031	.002	.002	3	11
BONE	Positive regulation of cytokinesis →	+0.140	+0.865	.008	<.001	2	12
BONE	Response to dehydroepiandrosterone →	+0.164	+0.704	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,506 associations by consensus.

Spindle elongation by HDGF expression — BLOOD_Lymphoma

Explore this box plot interactively →