HDAC7

Across TCGA patient cohorts, HDAC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,518 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDAC7-associated proteins across cancer lineages are HDAC7_S155, TLN1_S2040, and PRELP. Each is linked with HDAC7 in more than 6 cancer types. Because this analysis shows association rather than direction, both HDAC7-to-partner and partner-to-HDAC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC7 versus HDAC7_S155 in UCEC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC7→partner) and Y-score (partner→HDAC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HDAC7_S155 →	+0.519	+0.718	<.001	<.001	3	7
BRCA	TLN1_S2040 →	+0.744	+0.660	<.001	<.001	3	4
BRCA	PRELP →	+0.760	+0.611	<.001	<.001	3	4
BRCA	RPL5 →	-0.191	-0.510	<.001	.001	3	4
BRCA	BGN →	+0.788	+0.649	<.001	<.001	3	4
BRCA	CAVIN1 →	+0.819	+0.865	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,518 associations by consensus.

HDAC7 vs HDAC7_S155 — UCEC

Explore this scatter interactively →