HDAC7

Across TCGA patient cohorts, HDAC7 protein abundance is significantly associated with the RNA expression of many other genes, with 17,479 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDAC7-associated genes across cancer lineages are ELK3, FSTL1, and LTBP2. Each is linked with HDAC7 in more than 5 cancer types. Because this analysis shows association rather than direction, both HDAC7-to-partner and partner-to-HDAC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC7 versus ELK3 in UCEC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC7→partner) and Y-score (partner→HDAC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ELK3 →	+0.512	+0.161	<.001	.006	3	6
CCRCC	FSTL1 →	+0.808	+0.153	.002	.002	3	6
CCRCC	LTBP2 →	+0.948	+0.139	.001	.003	3	6
GBM	CD93 →	+0.810	+0.172	<.001	<.001	3	6
BRCA	RHOJ →	+0.789	+0.248	<.001	<.001	3	6
UCEC	EMP1 →	+1.223	+0.318	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,479 associations by consensus.

HDAC7 vs ELK3 — UCEC

Explore this scatter interactively →