Across TCGA cell cohorts, HDAC2 RNA expression is significantly associated with the RNA expression of many other genes, with 10,952 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HDAC2-associated genes across cancer lineages are HSF2, BCLAF1, and TCP1. Each is linked with HDAC2 in more than 19 cancer types. Because this analysis shows association rather than direction, both HDAC2-to-partner and partner-to-HDAC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC2→partner) and Y-score (partner→HDAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	HSF2 →	+1.451	+1.121	<.001	<.001	3	20
BLOOD_Lymphoma	BCLAF1 →	+1.076	+0.930	<.001	<.001	3	20
BLOOD_Myeloma	TCP1 →	+1.216	+1.094	<.001	.001	3	20
BLOOD_Lymphoma	SYNCRIP →	+1.042	+0.905	<.001	<.001	3	20
BREAST	RNGTT →	+0.933	+1.012	<.001	<.001	3	19
BLOOD_Lymphoma	ZBTB24 →	+0.808	+0.894	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,952 associations by consensus.

Exploration

HDAC2 survival (RNA) · tumor vs normal (RNA) · all HDAC2 data types