HDAC2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HDAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,239 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HDAC2-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Regulation of chromosome segregation, and Centrosome cycle. Each is linked with HDAC2 in more than 18 cancer types. Because this analysis shows association rather than direction, both HDAC2-to-partner and partner-to-HDAC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC2→partner) and Y-score (partner→HDAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaDNA-templated DNA replication maintenance of fidelity →+0.118+1.087<.001<.001319
UPPER_AERODIGESTIVE_TRACTRegulation of chromosome segregation →+0.117+0.766<.001.001318
LARGE_INTESTINECentrosome cycle →+0.078+0.764<.001<.001318
BREASTProtein-DNA complex organization →+0.064+0.886<.001<.001318
KIDNEYRegulation of mitotic metaphase/anaphase transition →+0.130+1.040<.001<.001318
BREASTRegulation of sister chromatid segregation →+0.114+1.002<.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,239 associations by consensus.

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