HDAC11

Across TCGA patient cohorts, HDAC11 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,780 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDAC11-associated proteins across cancer lineages are EPB41L1, TUBB4B, and PTPRC. Each is linked with HDAC11 in more than 5 cancer types. Because this analysis shows association rather than direction, both HDAC11-to-partner and partner-to-HDAC11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC11 versus EPB41L1 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC11→partner) and Y-score (partner→HDAC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EPB41L1 →	+0.673	+0.867	<.001	<.001	3	6
PDAC	TUBB4B →	+0.524	+0.299	.002	.005	3	5
LSCC	PTPRC →	-0.433	-0.361	<.001	<.001	3	5
GBM	SRCIN1 →	+0.683	+0.534	<.001	<.001	3	5
BRCA	PLEKHA6 →	+0.461	+0.740	<.001	<.001	3	5
BRCA	RASSF2 →	-0.475	-0.805	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,780 associations by consensus.

HDAC11 vs EPB41L1 — BRCA

Explore this scatter interactively →