HDAC11

Across TCGA patient cohorts, HDAC11 protein abundance is significantly associated with the RNA expression of many other genes, with 6,842 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDAC11-associated genes across cancer lineages are ABAT, RPS20P20, and RECQL. Each is linked with HDAC11 in more than 3 cancer types. Because this analysis shows association rather than direction, both HDAC11-to-partner and partner-to-HDAC11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC11 versus ABAT in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC11→partner) and Y-score (partner→HDAC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ABAT →	+1.631	+0.497	<.001	<.001	3	3
PDAC	RPS20P20 →	-1.151	-0.782	.001	.007	3	3
PDAC	RECQL →	-0.660	-0.795	.003	.005	3	3
UCEC	REEP5 →	+0.633	+0.818	.008	.005	3	3
LUAD	C1QTNF7 →	+0.753	+0.259	<.001	.002	3	3
GBM	MTMR10 →	+0.489	+0.781	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,842 associations by consensus.

HDAC11 vs ABAT — BRCA

Explore this scatter interactively →