HDAC10

Across TCGA patient cohorts, HDAC10 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,455 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HDAC10-associated proteins across cancer lineages are EIF4EBP2_S65, QPRT, and UTP15. Each is linked with HDAC10 in more than 3 cancer types. Because this analysis shows association rather than direction, both HDAC10-to-partner and partner-to-HDAC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC10 versus EIF4EBP2_S65 in BRCA, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC10→partner) and Y-score (partner→HDAC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF4EBP2_S65 →	-0.584	-0.260	<.001	<.001	3	4
LSCC	QPRT →	-0.687	-0.255	<.001	<.001	3	3
LSCC	UTP15 →	+0.291	+0.184	<.001	.002	3	3
GBM	PRPF4B_S294 →	+0.521	+0.310	<.001	<.001	3	3
LSCC	RBM28 →	+0.370	+0.208	<.001	<.001	3	3
OV	SARM1 →	+0.369	+0.185	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,455 associations by consensus.

HDAC10 vs EIF4EBP2_S65 — BRCA

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