HDAC10

Across TCGA patient cohorts, HDAC10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,923 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDAC10-associated genes across cancer lineages are STMN1, MDC1, and OSCAR. Each is linked with HDAC10 in more than 4 cancer types. Because this analysis shows association rather than direction, both HDAC10-to-partner and partner-to-HDAC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC10 versus STMN1 in LSCC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC10→partner) and Y-score (partner→HDAC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STMN1 →	-0.891	-0.238	<.001	.002	3	5
LSCC	MDC1 →	-0.633	-0.321	<.001	<.001	3	5
COAD	OSCAR →	+1.255	+1.814	.002	<.001	3	4
GBM	SOX4 →	-1.144	-0.373	<.001	.001	3	4
LSCC	CENPO →	-0.552	-0.234	<.001	.005	3	4
LSCC	CCDC150 →	-0.620	-0.302	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,923 associations by consensus.

HDAC10 vs STMN1 — LSCC

Explore this scatter interactively →