HDAC10

Across TCGA patient cohorts, HDAC10 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,465 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDAC10-associated proteins across cancer lineages are RPLP0, CELSR1, and DDB2_S26. Each is linked with HDAC10 in more than 5 cancer types. Because this analysis shows association rather than direction, both HDAC10-to-partner and partner-to-HDAC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC10 versus RPLP0 in COAD, with a Pearson correlation of -0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC10→partner) and Y-score (partner→HDAC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPLP0 →	-0.483	-1.987	<.001	<.001	3	5
LSCC	CELSR1 →	+0.516	+0.287	<.001	.001	2	5
GBM	DDB2_S26 →	+0.683	+0.503	<.001	<.001	3	4
LSCC	STMN1 →	-0.701	-0.271	<.001	<.001	2	5
GBM	UBA7 →	+0.462	+0.552	<.001	<.001	3	4
LSCC	XPO5 →	-0.443	-0.234	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,465 associations by consensus.

HDAC10 vs RPLP0 — COAD

Explore this scatter interactively →