HCRTR2

Across TCGA patient cohorts, HCRTR2 RNA expression is significantly associated with the RNA expression of many other genes, with 9,949 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible HCRTR2-associated genes across cancer lineages are HMGCLL1, LRFN5, and ERC2. Each is linked with HCRTR2 in more than 11 cancer types. Because this analysis shows association rather than direction, both HCRTR2-to-partner and partner-to-HCRTR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCRTR2 versus HMGCLL1 in UCS, with a Pearson correlation of 0.65.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCRTR2→partner) and Y-score (partner→HCRTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	HMGCLL1 →	+1.390	+1.127	<.001	<.001	3	12
TGCT	LRFN5 →	+1.291	+0.319	<.001	<.001	3	12
LGG	ERC2 →	+0.939	+0.197	<.001	<.001	3	12
ESCA	DZIP1 →	+0.966	+0.070	<.001	<.001	3	12
LGG	SYT1 →	+2.173	+0.221	<.001	<.001	3	12
TGCT	SLIT2 →	+0.938	+0.182	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,949 associations by consensus.

HCRTR2 vs HMGCLL1 — UCS

Explore this scatter interactively →