HCRTR2

Across TCGA patient cohorts, HCRTR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,716 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HCRTR2-associated proteins across cancer lineages are RPS8, RCOR1_S460, and RELB. Each is linked with HCRTR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HCRTR2-to-partner and partner-to-HCRTR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCRTR2 versus RPS8 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCRTR2→partner) and Y-score (partner→HCRTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS8 →	-0.363	-0.142	<.001	<.001	3	3
LSCC	RCOR1_S460 →	-0.375	-0.277	<.001	.003	3	2
COAD	RELB →	-0.232	-0.047	.003	.006	3	2
GBM	RPS13 →	-0.221	-0.144	<.001	<.001	3	2
GBM	RPS28 →	-0.182	-0.119	.001	.001	3	2
LUAD	RRBP1_S573 →	-0.799	-0.113	.009	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,716 associations by consensus.

HCRTR2 vs RPS8 — GBM

Explore this scatter interactively →