HCRTR2

Across TCGA patient cohorts, HCRTR2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,277 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HCRTR2-associated genes across cancer lineages are IL16, C10orf99, and ATF3. Each is linked with HCRTR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HCRTR2-to-partner and partner-to-HCRTR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCRTR2 versus IL16 in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCRTR2→partner) and Y-score (partner→HCRTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL16 →	+1.028	+1.475	.003	.001	3	3
HNSC	C10orf99 →	+1.952	+0.316	<.001	.007	3	3
CCRCC	ATF3 →	+1.595	+0.434	<.001	.002	3	3
CCRCC	FOS →	+1.703	+0.599	<.001	<.001	3	3
GBM	CCL3 →	+1.504	+0.637	<.001	.002	3	3
OV	CLIP3 →	-1.430	-0.897	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,277 associations by consensus.

HCRTR2 vs IL16 — BRCA

Explore this scatter interactively →