HCRTR2

Across TCGA cell cohorts, HCRTR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 170 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HCRTR2-associated GO terms across cancer lineages are COPII-coated vesicle budding, Pharynx development, and Negative regulation of mRNA catabolic process. Each is linked with HCRTR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HCRTR2-to-partner and partner-to-HCRTR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle budding grouped by HCRTR2-low versus HCRTR2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HCRTR2→partner) and Y-score (partner→HCRTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	COPII-coated vesicle budding →	+0.073	+0.032	<.001	.005	3	3
SKIN	Pharynx development →	-0.645	-0.018	.006	.009	3	3
LUNG_SCLC	Negative regulation of mRNA catabolic process →	+0.038	+0.142	.008	.007	3	3
LUNG_SCLC	RNA splicing, via transesterification reactions →	+0.039	+0.144	.005	.006	3	3
LUNG_SCLC	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.039	+0.144	.006	.006	2	4
LUNG_SCLC	mRNA splicing, via spliceosome →	+0.039	+0.144	.006	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 170 associations by consensus.

COPII-coated vesicle budding by HCRTR2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →