Across TCGA patient cohorts, HCP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,454 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HCP5-associated proteins across cancer lineages are TAP1, TAPBP, and HLA-F. Each is linked with HCP5 in more than 9 cancer types. Because this analysis shows association rather than direction, both HCP5-to-partner and partner-to-HCP5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCP5→partner) and Y-score (partner→HCP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TAP1 →	+0.769	+1.059	<.001	<.001	3	10
UCEC	TAPBP →	+0.707	+0.963	<.001	<.001	3	10
HNSC	HLA-F →	+0.648	+0.677	<.001	<.001	3	10
OV	LAP3 →	+0.652	+1.405	<.001	<.001	3	10
UCEC	PSMB10 →	+0.515	+0.922	<.001	<.001	3	10
LUAD	PSMB5 →	-0.553	-0.875	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,454 associations by consensus.

Exploration

HCP5 survival (RNA) · tumor vs normal (RNA) · all HCP5 data types