Across TCGA patient cohorts, HCG4B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,154 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HCG4B-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, MDA-5 signaling pathway, and Canonical NF-kappaB signal transduction. Each is linked with HCG4B in more than 27 cancer types. Because this analysis shows association rather than direction, both HCG4B-to-partner and partner-to-HCG4B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG4B→partner) and Y-score (partner→HCG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	Cytoplasmic pattern recognition receptor signaling pathway →	+0.044	+1.324	<.001	.001	3	27
CHOL	MDA-5 signaling pathway →	+0.134	+1.215	<.001	<.001	2	28
CHOL	Canonical NF-kappaB signal transduction →	+0.041	+1.308	<.001	<.001	3	27
CHOL	Regulation of MDA-5 signaling pathway →	+0.106	+1.388	.001	<.001	2	27
LAML	Positive regulation of canonical NF-kappaB signal transduction →	+0.047	+0.778	<.001	<.001	3	26
CHOL	Tumor necrosis factor-mediated signaling pathway →	+0.046	+1.168	<.001	.006	1	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,154 associations by consensus.

Exploration

HCG4B survival (RNA) · tumor vs normal (RNA) · all HCG4B data types