Across TCGA patient cohorts, HCG4B mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HCG4B-associated genes across cancer lineages are SALL4P2, SELENOTP2, and RNA5SP414. Each is linked with HCG4B in more than 1 cancer types. Because this analysis shows association rather than direction, both HCG4B-to-partner and partner-to-HCG4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG4B→partner) and Y-score (partner→HCG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SALL4P2 →	+0.032	+5.436	<.001	.005	3	1
UCEC	SELENOTP2 →	+0.280	+4.233	<.001	.009	3	1
UCEC	RNA5SP414 →	+1.391	+4.840	<.001	.003	3	1
SKCM	RNU6-234P →	+0.498	+5.771	<.001	.003	3	1
UCEC	MIR4797 →	+1.117	+4.633	<.001	.004	3	1
UCEC	RNU6-1082P →	+0.506	+4.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

HCG4B survival (RNA) · tumor vs normal (RNA) · all HCG4B data types