Across TCGA patient cohorts, HCG27 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,905 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HCG27-associated proteins across cancer lineages are PHF1, PSMB6, and CD2. Each is linked with HCG27 in more than 4 cancer types. Because this analysis shows association rather than direction, both HCG27-to-partner and partner-to-HCG27 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG27→partner) and Y-score (partner→HCG27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PHF1 →	+0.330	+0.586	<.001	<.001	3	5
HNSC	PSMB6 →	-0.484	-0.809	<.001	<.001	3	5
HNSC	CD2 →	+0.763	+0.566	<.001	.001	3	5
LSCC	CYFIP2 →	+0.501	+0.420	<.001	<.001	3	5
UCEC	DOCK8 →	+0.504	+0.431	<.001	.002	3	5
GBM	USF1 →	+0.365	+0.431	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,905 associations by consensus.

Exploration

HCG27 survival (RNA) · tumor vs normal (RNA) · all HCG27 data types