Across TCGA cell cohorts, HCG27 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HCG27-associated genes across cancer lineages are DPRX, C10orf53, and ETDC. Each is linked with HCG27 in more than 1 cancer types. Because this analysis shows association rather than direction, both HCG27-to-partner and partner-to-HCG27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG27→partner) and Y-score (partner→HCG27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DPRX →	+0.029	+4.321	.002	.009	3	1
BLOOD_Lymphoma	C10orf53 →	+0.035	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ETDC →	+0.847	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

HCG27 survival (RNA) · tumor vs normal (RNA) · all HCG27 data types