HCG18

Across TCGA patient cohorts, HCG18 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,371 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HCG18-associated proteins across cancer lineages are GNL1, CTNNBL1, and DAXX. Each is linked with HCG18 in more than 6 cancer types. Because this analysis shows association rather than direction, both HCG18-to-partner and partner-to-HCG18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCG18 versus GNL1 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG18→partner) and Y-score (partner→HCG18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GNL1 →	+0.246	+0.397	<.001	<.001	3	7
OV	CTNNBL1 →	+0.226	+0.526	<.001	<.001	3	6
GBM	DAXX →	+0.284	+0.336	.002	.004	3	6
HNSC	DHX16 →	+0.247	+0.754	<.001	<.001	3	6
HNSC	DHX9 →	+0.220	+0.606	.001	.004	3	6
GBM	HDAC2 →	+0.259	+0.350	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,371 associations by consensus.

HCG18 vs GNL1 — LSCC

Explore this scatter interactively →