HCG17

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HCG17 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,457 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HCG17-associated proteins across cancer lineages are SFN, KLC4, and NDRG1. Each is linked with HCG17 in more than 3 cancer types. Because this analysis shows association rather than direction, both HCG17-to-partner and partner-to-HCG17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCG17 versus SFN in GBM, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG17→partner) and Y-score (partner→HCG17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSFN →-0.848-0.465.004.00534
OVKLC4 →+0.410+0.742<.001<.00133
LSCCNDRG1 →-0.534-0.285.003<.00133
GBMATAT1 →+0.501+0.694<.001<.00133
LSCCCRYBG2 →-0.585-0.309<.001<.00133
GBMCADM4 →+0.467+0.506.003.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,457 associations by consensus.

HCG17 vs SFN — GBM

Per-sample scatter of HCG17 vs SFN in GBM (Pearson r = -0.31).

Explore this scatter interactively →

Exploration