Across TCGA patient cohorts, HCG11 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,521 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HCG11-associated proteins across cancer lineages are DDAH2, PRKG1, and JAM3. Each is linked with HCG11 in more than 4 cancer types. Because this analysis shows association rather than direction, both HCG11-to-partner and partner-to-HCG11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG11→partner) and Y-score (partner→HCG11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDAH2 →	+0.375	+0.615	.001	.004	3	5
PDAC	PRKG1 →	+0.373	+0.448	<.001	<.001	3	4
PDAC	JAM3 →	+0.551	+0.460	<.001	.001	3	4
HNSC	PPIF →	-0.652	-0.948	<.001	<.001	3	4
UCEC	PPP1R14A →	+0.800	+0.706	.003	.009	3	4
GBM	PLS3 →	+0.479	+0.663	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,521 associations by consensus.

Exploration

HCG11 survival (RNA) · tumor vs normal (RNA) · all HCG11 data types