Across TCGA patient cohorts, HCG11 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HCG11-associated genes across cancer lineages are OR13F1, RNU6-701P, and RNU6-74P. Each is linked with HCG11 in more than 1 cancer types. Because this analysis shows association rather than direction, both HCG11-to-partner and partner-to-HCG11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG11→partner) and Y-score (partner→HCG11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR13F1 →	+0.111	+5.038	.009	.002	3	1
UCEC	RNU6-701P →	+0.591	+5.386	<.001	.001	3	1
UCEC	RNU6-74P →	+0.406	+4.484	<.001	.009	3	1
UCEC	RNU6-906P →	+0.769	+4.256	<.001	.008	3	1
UCEC	MIR218-2 →	+0.548	+4.852	<.001	.006	3	1
UCEC	TRAJ38 →	+1.206	+4.633	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

HCG11 survival (RNA) · tumor vs normal (RNA) · all HCG11 data types