HCFC2

Across TCGA patient cohorts, HCFC2 protein abundance is significantly associated with the protein abundance of many other proteins, with 30,462 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HCFC2-associated proteins across cancer lineages are KCTD12, SEPTIN7, and EEA1. Each is linked with HCFC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both HCFC2-to-partner and partner-to-HCFC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCFC2 versus KCTD12 in UCEC, with a Pearson correlation of 0.53.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC2→partner) and Y-score (partner→HCFC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KCTD12 →	+0.554	+0.263	<.001	<.001	3	5
UCEC	SEPTIN7 →	+0.330	+0.329	<.001	<.001	3	5
UCEC	EEA1 →	+0.314	+0.375	<.001	<.001	3	4
UCEC	ANXA6 →	+0.550	+0.271	<.001	<.001	3	4
PDAC	ARHGAP17 →	+0.178	+0.311	.001	.001	2	5
LUAD	AVL9 →	-0.292	-0.141	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,462 associations by consensus.

HCFC2 vs KCTD12 — UCEC

Explore this scatter interactively →