HCFC1

Across TCGA patient cohorts, HCFC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,243 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HCFC1-associated proteins across cancer lineages are SF3B3, DHX9, and NONO. Each is linked with HCFC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HCFC1-to-partner and partner-to-HCFC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCFC1 versus SF3B3 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC1→partner) and Y-score (partner→HCFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.223	+0.562	.003	<.001	3	6
LSCC	DHX9 →	+0.210	+0.525	<.001	<.001	3	6
PDAC	NONO →	+0.149	+0.397	<.001	.001	3	6
UCEC	RFC3 →	+0.218	+0.461	.005	.001	3	5
GBM	SF3B2 →	+0.147	+0.456	.002	<.001	3	5
LSCC	TRIM28_S697 →	+0.984	+0.722	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,243 associations by consensus.

HCFC1 vs SF3B3 — GBM

Explore this scatter interactively →