HCFC1

Across TCGA patient cohorts, HCFC1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,165 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HCFC1-associated genes across cancer lineages are TGIF2, NKRF, and MSL2. Each is linked with HCFC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HCFC1-to-partner and partner-to-HCFC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCFC1 versus TGIF2 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC1→partner) and Y-score (partner→HCFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TGIF2 →	+0.620	+0.174	<.001	<.001	3	8
UCEC	NKRF →	+0.561	+0.133	.006	.009	3	8
HNSC	MSL2 →	+0.675	+0.181	<.001	<.001	3	8
COAD	PCIF1 →	+0.592	+0.157	<.001	<.001	3	7
LSCC	SCML2 →	+1.199	+0.176	<.001	<.001	3	7
HNSC	JADE3 →	+0.612	+0.227	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,165 associations by consensus.

HCFC1 vs TGIF2 — HNSC

Explore this scatter interactively →