HCFC1

Across TCGA cell cohorts, HCFC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,686 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HCFC1-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Nucleic acid transport, and RNA transport. Each is linked with HCFC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both HCFC1-to-partner and partner-to-HCFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by HCFC1-low versus HCFC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC1→partner) and Y-score (partner→HCFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.076	+1.296	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.121	+1.158	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.121	+1.158	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Mitotic chromosome condensation →	+0.184	+1.006	<.001	<.001	3	19
BONE	Positive regulation of mitotic cytokinesis →	+0.185	+1.406	.001	<.001	3	19
BONE	Regulation of double-strand break repair →	+0.103	+1.195	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,686 associations by consensus.

Negative regulation of gene expression, epigenetic by HCFC1 expression — SOFT_TISSUE

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