HCAR2

Across TCGA patient cohorts, HCAR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,867 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HCAR2-associated proteins across cancer lineages are CAMP, ELANE, and AZU1. Each is linked with HCAR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both HCAR2-to-partner and partner-to-HCAR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCAR2 versus CAMP in GBM, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCAR2→partner) and Y-score (partner→HCAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAMP →	+1.695	+0.903	<.001	<.001	3	9
PDAC	ELANE →	+1.026	+1.167	<.001	<.001	3	9
GBM	AZU1 →	+1.066	+0.917	<.001	<.001	3	9
COAD	CRISP3 →	+0.975	+1.576	<.001	<.001	3	8
COAD	GCA →	+0.555	+1.414	<.001	<.001	3	8
BRCA	PRTN3 →	+1.253	+0.970	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,867 associations by consensus.

HCAR2 vs CAMP — GBM

Explore this scatter interactively →